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CAS Number: 1380087-89-7
InChiKey: QQDIFLSJMFDTCQ-FIFLTTCUSA-N
With limited ability to cross the blood–brain barrier
It has more than a 400-fold higher affinity for BCL-XL versus other prosurvival BCL-2 family members
SKF-83566 hydrobromide Size:10mg solid CAS Number: 1380087-89-7SKF 83566 hydrobromide is a potent, blood brain permeable and orally active D1 like dopamine receptor (D1DR) antagonist and a weaker competitive antagonist at the vascular 5 HT2 receptor (Ki=11 nM). SKF 83566 is a competitive DAT (dopamine transporter) inhibitor with an IC50 of 5. 7 M. SKF 83566 also shows selective inhibition for adenylyl cyclase 2 (AC2) over AC1 and AC5 in the isolated rabbit thoracic aorta. SKF 83566 can be used for the research of
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