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Formula: C21H28Cl2N2O2
3 nM) and 4 ng/mL (9
Chemical Name: 3-[(3R
It is very selective (IC50 >10 μM) against all of the AAA ATPases
Leucovorin (Calcium) tetrahydrofolate Formula: C21H28Cl2N2O2Leucovorin calcium is a n active metabolite of folic acid (also called folinic acid and citrovorum factor), which does not require metabolism by dihydrofolate reductase, the molecular target of folate antagonist type chemotherapeutic drugs. Leucovorin calcium counteracts the toxic effects of these medications, 'rescuing' the patient while permitting the antitumor activity of the folate antagonist. This agent also potentiates the effects of
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