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5 nM (mCCR2) in binding antagonism and 3
C-176 strongly reduces STING-mediated
Grossfeld GD
Sophocarpine (monohydrate) has been demonstrated to have anti-tumor activity in various cancer cells
Milademetan hioinosine 5 nM (mCCR2) in bindingMilademetan (DS 3032) is a specific and orally active MDM2 inhibitor for the research of acute myeloid leukemia (AML) or solid tumors. Milademetan (DS 3032) induces G1 cell cycle arrest, senescence and apoptosis. Product information CAS Number: 1398568 47 2 Molecular Weight: 618. 53 Formula: C30H34Cl2FN5O4 Chemical Name: (3'R,4'S,5'R) N [(3R,6S) 6 carbamoyloxan 3 yl] 6'' chloro 4' (2 chloro 3 fluoropyridin 4 yl) 4,4 dimethyl 2'' oxo 1'',2''
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