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K/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9
antitubercular
CAS Number: 2070009-72-0
Caulfield TR
Semapimod tetrahydrochloride (disodium salt) K/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9Semapimod tetrahydrochloride (CNI 1493), an inhibitor of proinflammatory cytokine production, can inhibit TNF , IL 1, and IL 6. Semapimod tetrahydrochloride inhibits TLR4 signaling (IC500. 3 M). Semapimod tetrahydrochloride inhibits p38 MAPK and nitric oxide production in macrophages. Semapimod tetrahydrochloride has potential in a variety of inflammatory and autoimmune disorders. Product information CAS Number: 164301 51 3 Molecular Weight: 890. 74
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