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ERK5-IN-2 Catalog No.:M21699-C Smiles: CC(C)(C)NS(=O)(=O)C1C=CC(=CC=1)NC(=O)[C@H](CC1C=CC=CC=1)NC(=O)C1C=CC(F)=CC=1

SKU: 27083677567

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Description

Smiles: CC(C)(C)NS(=O)(=O)C1C=CC(=CC=1)NC(=O)[C@H](CC1C=CC=CC=1)NC(=O)C1C=CC(F)=CC=1

Formula: C26H25F2N7O6S2

CAS Number: 2206736-04-9

InChi: InChI=1S/C7H18NO2P/c1-2-3-6-11(9

ERK5-IN-2 Catalog No.:M21699-C Smiles: CC(C)(C)NS(=O)(=O)C1C=CC(=CC=1)NC(=O)[C@H](CC1C=CC=CC=1)NC(=O)C1C=CC(F)=CC=1ERK5 IN 2 is an orally active, sub micromolar, selective ERK5 inhibitor with IC50s of 0. 82 M, 3 M for ERK5 and ERK5 MEF2D, respectively. ERK5 IN 2 does not interact with the BRD4 bromodomain. ERK5 IN 2 suppresses both tumor xenograft growth and basic fibroblast growth factor (bFGF) driven Matrigel plug angiogenesis. Product information CAS Number: 1888305 96 1 Molecular Weight: 388. 19 Formula: C17H11BrFN3O2 Chemical Name: 4 (2 bromo 6 fluorobenzoyl)

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