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Smiles: CN(C)NC(=O)CCC(O)=O
Ilginatinib hydrochloride shows potent inhibitory activity against cell lines JAK2V617F or MPLW515L mutations or the TEL-JAK2 fusion gene (expressing a constitutively activated JAK2) with IC50 of 11-120 nM
InChiKey: VHQVOTINPRYDAO-UHFFFAOYSA-N
3)4)65-50(69)19-27-76-24-6-23-75-25-7-26-77-49-31-44-42(30-48(49)74-5)46(18-22-62-44)78-47-17-16-40(28-43(47)60)67(39-14-12-38(59)13-15-39)56(73)58(20-21-58)55(61)72/h8-18
ARQ 621 Catalog No.:M19604-C Smiles: CN(C)NC(=O)CCC(O)=OARQ 621 is an allosteric, potent and selective inhibitor of Eg5, a microtubule based ATPase motor protein involved in cell division. Anti tumor activity. ARQ 621 is a kinesin inhibitor. Product information CAS Number: 1095253 39 6 Molecular Weight: 552. 43 Formula: C28H24Cl2FN5O2 Chemical Name: N (3 aminopropyl) 3 chloro N [(1R) 1 [7 chloro 4 oxo 3 (phenylamino) 3,4 dihydroquinazolin 2 yl]but 3 yn 1 yl] 2 fluorobenzamide Smiles:
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